BPC-157 + TB-500 (Wolverine Blend) 20mg
Research Blends, Research Peptide Pens, Tissue and Cell-Migration Research
One pre-filled 20mg research pen combining BPC-157 10mg and TB-500 10mg.
- Made fresh to order
- Batch documentation pending
- UK tracked delivery
- Order by 1pm on working days for same-day dispatch
- Results published when verified
Research Use Only
BPC-157 + TB-500 20mg, often called the Wolverine blend, combines two of the most studied research peptides, BPC-157 and TB-500, in one pre-filled research pen. Each pen contains 10 mg of each compound. Every Wolverine blend is prepared to order in the UK and shipped cold chain by tracked delivery.
BPC-157 and thymosin beta-4 have separate preclinical literatures and act through different pathways, which is why laboratories study them side by side. Read BPC-157 vs TB-500 for a fuller comparison, and peptide stacks explained for how research blends are put together. For a blend that also includes GHK-Cu, see GLOW or KLOW.
Blend composition
| BPC-157 | 10 mg · Synthetic 15-amino-acid peptide |
|---|---|
| TB-500 | 10 mg · Synthetic thymosin beta-4 fragment (Ac-LKKTETQ) |
| Total | 20 mg in one pre-filled research pen |
How each component is studied
The two peptides in the Wolverine blend act through different pathways in laboratory studies:
- BPC-157 is a stable 15-amino-acid sequence derived from a gastric protein. Cell and rat studies have examined it in models of blood-vessel growth, VEGFR2 signalling and tendon fibroblast migration.
- TB-500 is a synthetic seven-amino-acid fragment of thymosin beta-4 (Ac-LKKTETQ), the region of the protein that binds actin. The fragment and the full protein are studied in models of cell migration and new blood-vessel formation.
5 key research areas
- Angiogenesis and vascular signalling. BPC-157 has been linked to VEGFR2 activation, and thymosin beta-4 has been examined in animal models of new blood-vessel growth.
- Cell migration and actin dynamics. Thymosin beta-4 and its LKKTETQ motif bind actin in cells. BPC-157 has been studied for its effect on how tendon fibroblasts spread and migrate.
- Tendon and connective-tissue models. BPC-157 research includes rat tendon explant and fibroblast studies, and reviews of musculoskeletal soft-tissue models.
- Cardiac cell models. In mice, thymosin beta-4 activated integrin-linked kinase and was studied for its effect on cardiomyocyte migration and survival.
- Skin wound models. Both compounds appear in preclinical work on skin wound models in rats and mice.
Selected published research
Peer-reviewed studies and reviews on each component, with PubMed IDs:
- Seiwerth S, et al. (2021). Stable gastric pentadecapeptide BPC 157 and wound healing. Frontiers in Pharmacology. PMID 34267654
- Chang CH, et al. (2011). The promoting effect of pentadecapeptide BPC 157 on tendon healing involves tendon outgrowth, cell survival, and cell migration. Journal of Applied Physiology. PMID 21030672
- Hsieh MJ, et al. (2017). Therapeutic potential of pro-angiogenic BPC157 is associated with VEGFR2 activation and up-regulation. Journal of Molecular Medicine. PMID 27847966
- Malinda KM, et al. (1999). Thymosin beta4 accelerates wound healing. Journal of Investigative Dermatology. PMID 10469335
- Bock-Marquette I, et al. (2004). Thymosin beta4 activates integrin-linked kinase and promotes cardiac cell migration, survival and cardiac repair. Nature. PMID 15565145
- Goldstein AL, et al. (2012). Thymosin β4: a multi-functional regenerative peptide. Expert Opinion on Biological Therapy. PMID 22074294
These references describe laboratory and animal research on the individual compounds. None of them studied the Wolverine blend, and none is evidence of safety or effect in humans.
Why a single-batch blend
- Both compounds come from one batch, under one batch reference
- One Certificate of Analysis will cover the whole blend once independent testing is complete
- Fewer handling steps than preparing two separate compounds
- Consistent composition from one order to the next
What arrives
One pre-filled Apexion research pen
BPC-157 and TB-500, 10 mg each
Discreet and tamper-evident
Batch number on every pen; independent testing in progress
Preparation and UK dispatch
- Made fresh to order after checkout
- Prepared and quality checked before dispatch
- Tracked Royal Mail delivery across the UK
- UK-based product and documentation support
Simple, secure checkout
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Independent testing is in progress; results will be published only when verified evidence is available.
Research use only. The Wolverine blend is supplied for in-vitro laboratory research by qualified researchers. It is not a medicine, is not licensed by the MHRA, and is not intended for human or veterinary use, diagnosis or treatment.
| Content | 20 mg total, one pre-filled research pen |
|---|---|
| Purity | Independent testing in progress; results published on verification |
| Active ingredient | BPC-157 10 mg · TB-500 10 mg |
| CAS | 137525-51-0 (BPC-157) / not assigned (TB-500 fragment) |
| Molecular formula | C62H98N16O22 / C38H68N10O14 |
| Molecular weight | ~1419.5 / ~889.0 g/mol |
| Form | Pre-filled research pen (two-peptide blend) |
| Origin | UK-stocked, tracked Royal Mail dispatch |
| Intended use | Laboratory research only. Not for human consumption. |
Every Wolverine blend pen is made fresh after your order is placed, and each one is prepared and quality checked before dispatch. Independent third-party testing of the blend is under way. The batch Certificate of Analysis will be published here, and linked to your pen's batch number, as soon as results are verified. Read how we test and verify every batch on our Quality & Batch Verification page.
| Documentation status | Independent testing in progress |
|---|---|
| Test method | HPLC (purity and identity) |
| Analysis | Independent third-party laboratory, plus in-house QC on every pen |
| Verification | Batch number on every pen; COA linked by QR once published |
Storage conditions
- Shipped cold chain to keep the pen cool in transit
- Long-term: −20 °C in a temperature-controlled environment
- Short-term: keep cool and stable (2–8 °C) and away from direct light
- Keep the pen sealed when not in use
- Avoid repeated temperature changes (freeze–thaw cycles)
Handling guidance
- Check that the packaging and tamper seal are intact on arrival
- Handle as little as possible, using standard laboratory practice
- Record the batch number for traceability
- Follow any batch-specific guidance supplied with your order
What is the Wolverine blend?
The Wolverine blend is a two-peptide research blend of BPC-157 and TB-500, supplied as 20 mg in one pre-filled research pen. Each compound has its own published preclinical literature. It is for laboratory research only.
What is the difference between the Wolverine blend, GLOW and KLOW?
The Wolverine blend contains BPC-157 and TB-500. GLOW adds GHK-Cu to those two, and KLOW adds GHK-Cu and KPV. All three are single-batch blends supplied for research use only.
What ratio is used in the Wolverine blend?
Each pen contains BPC-157 10 mg and TB-500 10 mg, for 20 mg in total. Both compounds come from one batch under one batch reference.
Is the Wolverine blend independently tested?
Every Wolverine blend pen is made fresh after your order is placed, so each one is prepared and quality checked to order rather than taken from old stock. Independent third-party testing of the blend is under way, and the batch Certificate of Analysis will be published as soon as the results are verified. Each pen carries a batch number, so its documentation can be traced.
Can the Wolverine blend be used in humans or animals?
No. The Wolverine blend is not a medicine and is not licensed by the MHRA. It is supplied strictly for in-vitro laboratory research, and is not for human or veterinary use, diagnosis or treatment.
How should the Wolverine blend be stored?
The Wolverine blend is shipped cold chain. On arrival, keep the pen sealed and store it at −20 °C for long-term storage, away from heat and direct light. Handle it as little as possible and follow any batch-specific guidance supplied with your order.
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