CELL-MIGRATION RESEARCH
TB-500 10MG
Research Peptide Pens, Tissue and Cell-Migration Research
One pre-filled 10mg TB-500 research pen for laboratory studies of cell movement and tissue-related pathways.
£79.99Free UK tracked delivery from £100
Compare recovery optionsBPC-157, TB-500, Wolverine, GLOW and KLOW→
- Made fresh to order
- Batch documentation pending
- UK tracked delivery
- Order by 1pm on working days for same-day dispatch
- Results published when verified
Research Use Only
TB-500 10mg is a synthetic seven-amino-acid peptide, Ac-LKKTETQ, supplied in one pre-filled research pen. It matches residues 17 to 23 of thymosin beta-4, the stretch of that protein that binds actin, which makes it a common tool in cell-migration research. Every TB-500 pen is prepared to order in the UK and shipped cold chain by tracked delivery.
Thymosin beta-4 itself is a natural 43-amino-acid protein of about 4,963 g/mol, and much of the published research used the full protein, so each study below names the compound it tested. To see how it compares with the peptide it is most often paired with, read BPC-157 vs TB-500.
How TB-500 is studied
The LKKTETQ motif is the part of thymosin beta-4 that binds monomeric (G-) actin, which controls how much actin is available to build filaments and so how cells change shape and move. In endothelial cell migration assays, the motif and the full protein showed near-identical activity (Philp et al., 2003). Animal studies, mostly of full-length thymosin beta-4, have examined dermal wound models in rodents, mouse heart models where the protein activated integrin-linked kinase, and hair-follicle stem-cell models.
5 key research areas
- Actin dynamics and cell migration. The LKKTETQ motif binds G-actin, and cell studies have used the motif and full thymosin beta-4 to examine cell shape and endothelial cell migration.
- Angiogenesis and neovascularisation. Mouse studies of full-length thymosin beta-4 examined its role in the mobilisation of epicardial progenitor cells and the growth of new coronary vessels.
- Cardiac cell models. In mice, full-length thymosin beta-4 activated integrin-linked kinase and was studied for its effect on cardiomyocyte migration and survival after coronary ligation.
- Dermal wound models. Rat and mouse studies, including diabetic and aged mice, tested full-length thymosin beta-4 and a peptide containing its actin-binding domain in wound-closure models.
- Hair-follicle stem cells. Rodent work studied full-length thymosin beta-4 in the activation and migration of hair-follicle stem cells.
Selected published research
Peer-reviewed studies and reviews on thymosin beta-4, with PubMed IDs:
- Malinda KM, et al. (1999). Thymosin beta4 accelerates wound healing. Journal of Investigative Dermatology. PMID 10469335
- Philp D, et al. (2003). Thymosin beta 4 and a synthetic peptide containing its actin-binding domain promote dermal wound repair in db/db diabetic mice and in aged mice. Wound Repair and Regeneration. PMID 12581423
- Bock-Marquette I, et al. (2004). Thymosin beta4 activates integrin-linked kinase and promotes cardiac cell migration, survival and cardiac repair. Nature. PMID 15565145
- Philp D, et al. (2004). Thymosin beta4 increases hair growth by activation of hair follicle stem cells. FASEB Journal. PMID 14657002
- Smart N, et al. (2007). Thymosin beta4 induces adult epicardial progenitor mobilization and neovascularization. Nature. PMID 17108969
- Goldstein AL, et al. (2012). Thymosin β4: a multi-functional regenerative peptide. Expert Opinion on Biological Therapy. PMID 22074294
These references describe laboratory and animal research on thymosin beta-4 and its actin-binding fragment. None of them is evidence of safety or effect in humans.
What arrives
10mg pen
One pre-filled Apexion research pen
One pre-filled Apexion research pen
Single compound
TB-500, thymosin beta-4 fragment (Ac-LKKTETQ)
TB-500, thymosin beta-4 fragment (Ac-LKKTETQ)
Protected packaging
Discreet and tamper-evident
Discreet and tamper-evident
Batch traceability
Batch number on every pen; independent testing in progress
Batch number on every pen; independent testing in progress
Preparation and UK dispatch
- Made fresh to order after checkout
- Prepared and quality checked before dispatch
- Tracked Royal Mail delivery across the UK
- UK-based product and documentation support
Simple, secure checkout
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Independent testing is in progress; results will be published only when verified evidence is available.
Source-material testing record
The submitted source-material report measured 10.65 mg TB-500 (TB4) and reported 99.015% purity.
Scope: This information concerns a submitted source-material sample. It does not certify an Apexion finished pen or establish a match to the pen batch.
View source-material record (PDF) →
The original laboratory report is available on request.
Research use only. TB-500 is supplied for in-vitro laboratory research by qualified researchers. It is not a medicine, is not licensed by the MHRA, and is not intended for human or veterinary use, diagnosis or treatment.
| Content | 10 mg TB-500, one pre-filled research pen |
|---|---|
| Purity | Independent testing in progress; results published on verification |
| CAS | Not assigned (77591-33-4 is full-length thymosin beta-4) |
| Molecular formula | C38H68N10O14 (Ac-LKKTETQ) |
| Molecular weight | ~889.0 g/mol |
| Form | Pre-filled research pen |
| Origin | UK-stocked, tracked Royal Mail dispatch |
| Intended use | Laboratory research only. Not for human consumption. |
APEXION BIOLABS
Quality & Verification
Batch Verification Record
Independent analytical documentation for TB-500 10 mg.
Verification statusSource-material report reviewed
Product & Record
| Product | TB-500 10 mg |
|---|---|
| Apexion verification ID | AX-QV-TB500-001 |
| Analytical laboratory | Janoshik Analytical |
| Documentation status | Original laboratory report available on request |
| Finished pen batch testing | In progress. Results will be published here once verified. |
Documented Analytical Information
| Material tested | Lyophilised source material |
|---|---|
| Purity specification | 99.015% (reported purity) |
| Independent analysis | Analysis by Janoshik Analytical, 24 Apr 2026 |
| TB-500 (TB4) | 10.65 mg |
| Reported purity | 99.015% |
Verification Statement
Apexion BioLabs has summarised the supplied independent laboratory information for a source-material sample. The original report is retained separately and is not altered or re-issued as an Apexion laboratory certificate.
Documentation Transparency
The values apply to the submitted source-material sample, not an Apexion finished pen.
The source-material result does not certify an Apexion finished pen or establish a match to any Apexion product batch. Supplier identity and supply-chain identifiers are omitted from this customer summary; originals are available for verification.
Independent lab analysisSupporting documentationApexion verification record
Apexion BioLabs – Batch Verification RecordAX-QV-TB500-001
| Documentation status | Independent source-material analysis available (Janoshik Analytical); finished-pen batch testing in progress |
|---|---|
| Test method | HPLC (purity and identity) |
| Analysis | Janoshik Analytical (independent laboratory) on a source-material sample; testing of finished pen batches is in progress |
| Verification | Apexion verification record AX-QV-TB500-001; the original laboratory report is retained by Apexion and available on request |
Storage conditions
- Shipped cold chain to keep the pen cool in transit
- Long-term: −20 °C in a temperature-controlled environment
- Short-term: keep cool and stable (2–8 °C) and away from direct light
- Keep the pen sealed when not in use
- Avoid repeated temperature changes (freeze–thaw cycles)
Handling guidance
- Check that the packaging and tamper seal are intact on arrival
- Handle as little as possible, using standard laboratory practice
- Record the batch number for traceability
- Follow any batch-specific guidance supplied with your order
What is TB-500?
TB-500 is a synthetic seven-amino-acid peptide, Ac-LKKTETQ, copied from the actin-binding region of thymosin beta-4. It is studied in cell and animal models of cell migration, and much of the related literature used the full protein. Apexion supplies it for laboratory research only.
Is TB-500 the same as thymosin beta-4?
No. Thymosin beta-4 is a natural 43-amino-acid protein of about 4,963 g/mol. TB-500 is a synthetic fragment of it, Ac-LKKTETQ, at about 889 g/mol. The formula and molecular weight on this page are those of the fragment, and the mass result on the batch COA confirms which molecule a pen holds.
What is the difference between TB-500 and BPC-157?
TB-500 is a seven-amino-acid fragment of thymosin beta-4 that binds actin and is studied in cell-migration models. BPC-157 is a 15-amino-acid peptide studied mainly for VEGFR2 signalling and tendon fibroblast behaviour. We supply both separately and together as the BPC-157 + TB-500 Wolverine blend.
Is TB-500 independently tested?
Every TB-500 pen is made fresh after your order is placed, so each one is prepared and quality checked to order rather than taken from old stock. Independent third-party testing of TB-500 is under way, and the batch Certificate of Analysis will be published as soon as the results are verified. Each pen carries a batch number, so its documentation can be traced.
Can TB-500 be used in humans or animals?
No. TB-500 is not a medicine and is not licensed by the MHRA. It is supplied strictly for in-vitro laboratory research, and is not for human or veterinary use, diagnosis or treatment.
How should TB-500 be stored?
TB-500 is shipped cold chain. On arrival, keep the pen sealed and store it at −20 °C for long-term storage, away from heat and direct light. Handle it as little as possible and follow any batch-specific guidance supplied with your order.
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