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4-PEPTIDE RESEARCH BLEND

KLOW 80MG

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One pre-filled 80mg KLOW research pen containing BPC-157, TB-500, KPV and GHK-Cu.

4.9 · 20 Google reviews Research grade
£175.00Free UK tracked delivery
Compare recovery optionsBPC-157, TB-500, Wolverine, GLOW and KLOW
  • Made fresh to order
  • Batch documentation pending
  • UK tracked delivery
  • Order by 1pm on working days for same-day dispatch
  • Results published when verified

Research Use Only

KLOW 80mg is a four-peptide research blend of GHK-Cu, BPC-157, TB-500 and KPV, supplied in one pre-filled research pen. It extends the three-peptide “GLOW” combination (GHK-Cu, BPC-157 and TB-500) with KPV, a tripeptide studied in inflammatory-signalling models. Every KLOW blend is prepared to order in the UK and sent by tracked delivery.

Each of the four compounds has its own published preclinical literature. Laboratories use multi-peptide blends to study how separate signalling pathways behave within the same in-vitro or animal model. New to KPV? Read what KPV is and how it differs from the other three.

Blend composition

GHK-Cu 50 mg · Copper-binding tripeptide (Gly-His-Lys:Cu²⁺)
BPC-157 10 mg · Synthetic 15-amino-acid peptide
TB-500 10 mg · Synthetic thymosin beta-4 fragment (Ac-LKKTETQ)
KPV 10 mg · Tripeptide (Lys-Pro-Val), C-terminal fragment of alpha-MSH
Total 80 mg in one pre-filled research pen

How each component is studied

The four peptides in KLOW act through different pathways in laboratory studies:

  • BPC-157 is a stable 15-amino-acid sequence derived from a gastric protein. Animal and cell studies have examined it in models of blood-vessel growth, fibroblast migration and tissue-repair signalling.
  • TB-500 is a synthetic seven-amino-acid fragment of thymosin beta-4 (Ac-LKKTETQ), the region of the protein that binds actin. The fragment and the full protein are studied in models of cell migration and new blood-vessel formation.
  • KPV is a three-amino-acid fragment of alpha-MSH. Cell and mouse studies have examined its effect on inflammatory signalling, including the NF-κB and MAPK pathways.
  • GHK-Cu is a naturally occurring copper-binding tripeptide. Gene-expression studies link it to collagen production, extracellular-matrix remodelling and many other cellular pathways.

5 key research areas

  1. Angiogenesis and vascular signalling. BPC-157 and thymosin beta-4 have both been examined in animal models of blood-vessel growth.
  2. Cell migration and actin dynamics. Thymosin beta-4 and its LKKTETQ motif bind actin in cells. BPC-157 has been studied for its effect on how tendon fibroblasts spread and migrate.
  3. Inflammatory signalling. KPV research focuses on NF-κB activity, cytokine release and the PepT1 transporter in intestinal cell and mouse colitis models.
  4. Extracellular matrix and gene expression. GHK-Cu studies cover collagen and glycosaminoglycan synthesis and large-scale gene-expression data.
  5. Wound and connective-tissue models. All four compounds appear in preclinical work on skin wound, tendon and connective-tissue models.

Selected published research

Peer-reviewed studies and reviews on each KLOW component, with PubMed IDs:

  1. Seiwerth S, et al. (2021). Stable gastric pentadecapeptide BPC 157 and wound healing. Frontiers in Pharmacology. PMID 34267654
  2. Chang CH, et al. (2011). The promoting effect of pentadecapeptide BPC 157 on tendon healing involves tendon outgrowth, cell survival, and cell migration. Journal of Applied Physiology. PMID 21030672
  3. Malinda KM, et al. (1999). Thymosin beta4 accelerates wound healing. Journal of Investigative Dermatology. PMID 10469335
  4. Bock-Marquette I, et al. (2004). Thymosin beta4 activates integrin-linked kinase and promotes cardiac cell migration, survival and cardiac repair. Nature. PMID 15565145
  5. Goldstein AL, et al. (2012). Thymosin β4: a multi-functional regenerative peptide. Expert Opinion on Biological Therapy. PMID 22074294
  6. Dalmasso G, et al. (2008). PepT1-mediated tripeptide KPV uptake reduces intestinal inflammation. Gastroenterology. PMID 18061177
  7. Kannengiesser K, et al. (2008). Melanocortin-derived tripeptide KPV has anti-inflammatory potential in murine models of inflammatory bowel disease. Inflammatory Bowel Diseases. PMID 18092346
  8. Pickart L, et al. (2015). GHK peptide as a natural modulator of multiple cellular pathways in skin regeneration. BioMed Research International. PMID 26236730
  9. Pickart L, Margolina A (2018). Regenerative and protective actions of the GHK-Cu peptide in the light of the new gene data. International Journal of Molecular Sciences. PMID 29986520

These references describe laboratory and animal research on the individual compounds. None of them studied the KLOW blend, and none is evidence of safety or effect in humans.

Why a single-batch blend

  • All four compounds come from one batch, under one batch reference
  • One Certificate of Analysis will cover the whole blend once independent testing is complete
  • Fewer handling steps than preparing four separate compounds
  • Consistent composition from one order to the next

What arrives

80mg blend pen
One pre-filled Apexion research pen
Four-compound blend
GHK-Cu, BPC-157, TB-500 and KPV
Protected packaging
Discreet and tamper-evident
Batch traceability
Batch number on every pen; independent testing in progress

Preparation and UK dispatch

  • Made fresh to order after checkout
  • Prepared and quality checked before dispatch
  • Tracked Royal Mail delivery across the UK
  • UK-based product and documentation support

Simple, secure checkout

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Independent testing is in progress; results will be published only when verified evidence is available.

Research use only. KLOW is supplied for in-vitro laboratory research by qualified researchers. It is not a medicine, is not licensed by the MHRA, and is not intended for human or veterinary use, diagnosis or treatment.

Research gradeLaboratory use only
Analytical statusIndependent testing in progress; results published on verification
Research use onlyNot for human consumption
Product presentation
KLOW 80MG

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Compare with GLOW 70MG

This product KLOW 80MG GLOW 70MG
Contents 80 mg total, one pre-filled research pen 70 mg total, one pre-filled research pen
Compounds GHK-Cu 50 mg · BPC-157 10 mg · TB-500 10 mg · KPV 10 mg GHK-Cu 50 mg · BPC-157 10 mg · TB-500 10 mg
Format Pre-filled research pen (four-peptide blend) Pre-filled research pen (three-peptide blend)
Price £175.00 £159.00
Price per mg £2.19 £2.27
Independent testing Independent testing in progress Independent testing in progress
View GLOW 70MG

Price per mg is the price divided by the total labelled contents. For laboratory research use only.

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