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CELLULAR ENERGY RESEARCH

NAD+ 500MG

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One pre-filled 1000mg NAD+ research pen for laboratory studies of cellular energy processes.

4.9 · 20 Google reviews Research grade
£149.99Free UK tracked delivery
Compare cellular-energy optionsMOTS-C, NAD+ and SS-31
  • Made fresh to order
  • Batch documentation pending
  • UK tracked delivery
  • Order by 1pm on working days for same-day dispatch
  • Results published when verified

Research Use Only

NAD+ 500mg (nicotinamide adenine dinucleotide) is the oxidised form of a coenzyme found in every living cell, supplied in one pre-filled research pen. Every NAD+ pen is prepared to order in the UK and shipped cold chain by tracked delivery.

NAD+ is not a peptide but a dinucleotide, and it sits at the centre of cellular energy metabolism. Read MOTS-c vs SS-31 vs NAD+ for how it compares with the mitochondrial peptides MOTS-c and SS-31, or see 5-Amino-1MQ, a compound studied for its effect on the NAD+ salvage pathway.

How NAD+ is studied

NAD+ carries electrons in glycolysis, the citric acid cycle and oxidative phosphorylation, cycling between its oxidised (NAD+) and reduced (NADH) forms. It is also consumed as a substrate by sirtuins, PARP enzymes and CD38, which link it to gene regulation and DNA-damage signalling. Animal studies have measured NAD+ levels in different tissues with age and examined precursors such as NMN and NR.

5 key research areas

  1. Redox metabolism. NAD+ and NADH are studied as electron carriers in glycolysis, the citric acid cycle and mitochondrial respiration.
  2. Sirtuin signalling. Sirtuins are NAD+-dependent deacylases, so NAD+ availability is examined as a regulator of their activity.
  3. PARP and DNA-damage signalling. PARP enzymes consume NAD+ when they respond to DNA damage, linking NAD+ levels to genome-maintenance research.
  4. Age-related changes in NAD+ levels. Rodent studies have measured how NAD+ levels change across tissues with age, and the role of NAD+-consuming enzymes such as CD38.
  5. Precursors and biosynthesis. The salvage pathway and precursors such as NMN and NR are studied for how they raise cellular NAD+ in animal models.

Selected published research

Peer-reviewed reviews on NAD+ biology, with PubMed IDs:

  1. Imai S, Guarente L (2014). NAD+ and sirtuins in aging and disease. Trends in Cell Biology. PMID 24786309
  2. Verdin E (2015). NAD⁺ in aging, metabolism, and neurodegeneration. Science. PMID 26785480
  3. Yoshino J, et al. (2018). NAD(+) intermediates: the biology and therapeutic potential of NMN and NR. Cell Metabolism. PMID 29249689
  4. Rajman L, et al. (2018). Therapeutic potential of NAD-boosting molecules: the in vivo evidence. Cell Metabolism. PMID 29514064
  5. Covarrubias AJ, et al. (2021). NAD(+) metabolism and its roles in cellular processes during ageing. Nature Reviews Molecular Cell Biology. PMID 33353981

These references describe laboratory and animal research on NAD+ and its precursors. They are cited as scientific background only and do not make this research material suitable for human use.

What arrives

500mg pen
One pre-filled Apexion research pen
Single compound
NAD+, nicotinamide adenine dinucleotide
Protected packaging
Discreet and tamper-evident
Batch traceability
Batch number on every pen; independent testing in progress

Preparation and UK dispatch

  • Made fresh to order after checkout
  • Prepared and quality checked before dispatch
  • Tracked Royal Mail delivery across the UK
  • UK-based product and documentation support

Simple, secure checkout

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Independent testing is in progress; results will be published only when verified evidence is available.

Research use only. This product is supplied for in-vitro laboratory research by qualified researchers. It is not a medicine, is not licensed by the MHRA, and is not intended for human or veterinary use, diagnosis or treatment.

Research gradeLaboratory use only
Analytical statusIndependent testing in progress; results published on verification
Research use onlyNot for human consumption
Product presentation
NAD+ 500MG

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