NAD+ 500MG
Mitochondrial and Cellular Energy Research, Research Peptide Pens
One pre-filled 1000mg NAD+ research pen for laboratory studies of cellular energy processes.
- Made fresh to order
- Batch documentation pending
- UK tracked delivery
- Order by 1pm on working days for same-day dispatch
- Results published when verified
Research Use Only
NAD+ 500mg (nicotinamide adenine dinucleotide) is the oxidised form of a coenzyme found in every living cell, supplied in one pre-filled research pen. Every NAD+ pen is prepared to order in the UK and shipped cold chain by tracked delivery.
NAD+ is not a peptide but a dinucleotide, and it sits at the centre of cellular energy metabolism. Read MOTS-c vs SS-31 vs NAD+ for how it compares with the mitochondrial peptides MOTS-c and SS-31, or see 5-Amino-1MQ, a compound studied for its effect on the NAD+ salvage pathway.
How NAD+ is studied
NAD+ carries electrons in glycolysis, the citric acid cycle and oxidative phosphorylation, cycling between its oxidised (NAD+) and reduced (NADH) forms. It is also consumed as a substrate by sirtuins, PARP enzymes and CD38, which link it to gene regulation and DNA-damage signalling. Animal studies have measured NAD+ levels in different tissues with age and examined precursors such as NMN and NR.
5 key research areas
- Redox metabolism. NAD+ and NADH are studied as electron carriers in glycolysis, the citric acid cycle and mitochondrial respiration.
- Sirtuin signalling. Sirtuins are NAD+-dependent deacylases, so NAD+ availability is examined as a regulator of their activity.
- PARP and DNA-damage signalling. PARP enzymes consume NAD+ when they respond to DNA damage, linking NAD+ levels to genome-maintenance research.
- Age-related changes in NAD+ levels. Rodent studies have measured how NAD+ levels change across tissues with age, and the role of NAD+-consuming enzymes such as CD38.
- Precursors and biosynthesis. The salvage pathway and precursors such as NMN and NR are studied for how they raise cellular NAD+ in animal models.
Selected published research
Peer-reviewed reviews on NAD+ biology, with PubMed IDs:
- Imai S, Guarente L (2014). NAD+ and sirtuins in aging and disease. Trends in Cell Biology. PMID 24786309
- Verdin E (2015). NAD⁺ in aging, metabolism, and neurodegeneration. Science. PMID 26785480
- Yoshino J, et al. (2018). NAD(+) intermediates: the biology and therapeutic potential of NMN and NR. Cell Metabolism. PMID 29249689
- Rajman L, et al. (2018). Therapeutic potential of NAD-boosting molecules: the in vivo evidence. Cell Metabolism. PMID 29514064
- Covarrubias AJ, et al. (2021). NAD(+) metabolism and its roles in cellular processes during ageing. Nature Reviews Molecular Cell Biology. PMID 33353981
These references describe laboratory and animal research on NAD+ and its precursors. They are cited as scientific background only and do not make this research material suitable for human use.
What arrives
One pre-filled Apexion research pen
NAD+, nicotinamide adenine dinucleotide
Discreet and tamper-evident
Batch number on every pen; independent testing in progress
Preparation and UK dispatch
- Made fresh to order after checkout
- Prepared and quality checked before dispatch
- Tracked Royal Mail delivery across the UK
- UK-based product and documentation support
Simple, secure checkout
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Independent testing is in progress; results will be published only when verified evidence is available.
Research use only. This product is supplied for in-vitro laboratory research by qualified researchers. It is not a medicine, is not licensed by the MHRA, and is not intended for human or veterinary use, diagnosis or treatment.
| Content | 500 mg NAD+, one pre-filled research pen |
|---|---|
| Purity | Independent testing in progress; results published on verification |
| CAS | 53-84-9 |
| Molecular formula | C21H27N7O14P2 |
| Molecular weight | ~663.4 g/mol |
| Form | Pre-filled research pen |
| Origin | UK-stocked, tracked Royal Mail dispatch |
| Intended use | Laboratory research only. Not for human consumption. |
Every NAD+ pen is made fresh after your order is placed, and each one is prepared and quality checked before dispatch. Independent third-party testing of NAD+ is under way. The batch Certificate of Analysis will be published here, and linked to your pen's batch number, as soon as results are verified. Read how we test and verify every batch on our Quality & Batch Verification page.
| Documentation status | Independent testing in progress |
|---|---|
| Test method | HPLC (purity and identity) |
| Analysis | Independent third-party laboratory, plus in-house QC on every pen |
| Verification | Batch number on every pen; COA linked by QR once published |
Storage conditions
- Shipped cold chain to keep the pen cool in transit
- Long-term: −20 °C in a temperature-controlled environment
- Short-term: keep cool and stable (2–8 °C) and away from direct light
- Keep the pen sealed when not in use
- Avoid repeated temperature changes (freeze–thaw cycles)
Handling guidance
- Check that the packaging and tamper seal are intact on arrival
- Handle as little as possible, using standard laboratory practice
- Record the batch number for traceability
- Follow any batch-specific guidance supplied with your order
What is NAD+?
NAD+ (nicotinamide adenine dinucleotide) is a coenzyme found in every living cell. It carries electrons in energy metabolism and is used by enzymes such as sirtuins and PARPs. Apexion supplies it for laboratory research only.
Is NAD+ a peptide?
No. NAD+ is a dinucleotide made of two nucleotides joined through their phosphate groups. It is supplied in the same pre-filled research pen format as our peptides.
How much NAD+ is in each pen?
Each pen contains 500 mg of NAD+ in one pre-filled research pen. Every pen comes from a single batch and carries its batch number.
Is NAD+ independently tested?
Every NAD+ pen is made fresh after your order is placed, so each one is prepared and quality checked to order rather than taken from old stock. Independent third-party testing of NAD+ is under way, and the batch Certificate of Analysis will be published as soon as the results are verified. Each pen carries a batch number, so its documentation can be traced.
Can NAD+ be used in humans or animals?
No. This product is not a medicine and is not licensed by the MHRA. It is supplied strictly for in-vitro laboratory research, and is not for human or veterinary use, diagnosis or treatment.
How should NAD+ be stored?
NAD+ is shipped cold chain. On arrival, keep the pen sealed and store it at −20 °C for long-term storage, away from heat and direct light. Handle it as little as possible and follow any batch-specific guidance supplied with your order.
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