NAD+ 500MG
MITOCHONDRIAL RESEARCH
SS-31 50MG
Mitochondrial and Cellular Energy Research, Research Peptide Pens
One pre-filled 30mg SS-31 research pen for laboratory studies of cellular energy processes.
£139.99Free UK tracked delivery
Compare cellular-energy optionsMOTS-C, NAD+ and SS-31→
- Made fresh to order
- Batch documentation pending
- UK tracked delivery
- Order by 1pm on working days for same-day dispatch
- Results published when verified
Research Use Only
SS-31 50mg (elamipretide) is a synthetic tetrapeptide, D-Arg-Dmt-Lys-Phe-NH2, that targets the inner mitochondrial membrane, supplied in one pre-filled research pen. Every SS-31 pen is prepared to order in the UK and shipped cold chain by tracked delivery.
SS-31 belongs to the Szeto-Schiller family of cell-permeable peptides and is one of the most studied mitochondria-targeted compounds. Read our SS-31 research overview, or compare it with MOTS-c and NAD+ in MOTS-c vs SS-31 vs NAD+.
How SS-31 is studied
SS-31 carries alternating aromatic and basic amino acids, which let it cross cell membranes and concentrate at the inner mitochondrial membrane. There it binds cardiolipin, a phospholipid that supports the structure of the electron transport chain. Cell and animal studies have examined its effects on mitochondrial swelling, reactive oxygen species, ATP production and the energetics of aged skeletal muscle.
5 key research areas
- Cardiolipin binding. Studies examined how SS-31 interacts with cardiolipin and how this affects cristae structure and electron transport.
- Oxidative stress models. Early cell and animal work studied SS-31 in models of mitochondrial swelling, oxidative cell death and ischaemia-reperfusion.
- Mitochondrial energetics. Kidney ischaemia models examined ATP production and mitochondrial respiration in the presence of SS-31.
- Aged skeletal muscle. Mouse studies measured mitochondrial energetics and muscle performance in aged animals.
- Protein interaction mapping. Cross-linking mass spectrometry mapped the mitochondrial proteins that SS-31 interacts with.
Selected published research
Peer-reviewed studies on SS-31, with PubMed IDs:
- Zhao K, et al. (2004). Cell-permeable peptide antioxidants targeted to inner mitochondrial membrane inhibit mitochondrial swelling, oxidative cell death, and reperfusion injury. Journal of Biological Chemistry. PMID 15178689
- Birk AV, et al. (2013). The mitochondrial-targeted compound SS-31 re-energizes ischemic mitochondria by interacting with cardiolipin. Journal of the American Society of Nephrology. PMID 23813215
- Siegel MP, et al. (2013). Mitochondrial-targeted peptide rapidly improves mitochondrial energetics and skeletal muscle performance in aged mice. Aging Cell. PMID 23692570
- Szeto HH (2014). First-in-class cardiolipin-protective compound as a therapeutic agent to restore mitochondrial bioenergetics. British Journal of Pharmacology. PMID 24117165
- Chavez JD, et al. (2020). Mitochondrial protein interaction landscape of SS-31. Proceedings of the National Academy of Sciences of the USA. PMID 32554501
These references describe laboratory and animal research on SS-31, also known as elamipretide. They are cited as scientific background only and do not make this research material suitable for human use.
What arrives
50mg pen
One pre-filled Apexion research pen
One pre-filled Apexion research pen
Single compound
SS-31 (elamipretide), mitochondria-targeted tetrapeptide
SS-31 (elamipretide), mitochondria-targeted tetrapeptide
Protected packaging
Discreet and tamper-evident
Discreet and tamper-evident
Batch traceability
Batch number on every pen; independent testing in progress
Batch number on every pen; independent testing in progress
Preparation and UK dispatch
- Made fresh to order after checkout
- Prepared and quality checked before dispatch
- Tracked Royal Mail delivery across the UK
- UK-based product and documentation support
Simple, secure checkout
Pay by Bank is the preferred option
Card payments are temporarily unavailable.
Card payments are temporarily unavailable.
Independent testing is in progress; results will be published only when verified evidence is available.
Research use only. This product is supplied for in-vitro laboratory research by qualified researchers. It is not a medicine, is not licensed by the MHRA, and is not intended for human or veterinary use, diagnosis or treatment.
| Content | 50 mg SS-31, one pre-filled research pen |
|---|---|
| Purity | Independent testing in progress; results published on verification |
| CAS | 736992-21-5 |
| Molecular formula | C32H49N9O5 |
| Molecular weight | ~639.8 g/mol |
| Form | Pre-filled research pen |
| Origin | UK-stocked, tracked Royal Mail dispatch |
| Intended use | Laboratory research only. Not for human consumption. |
Every SS-31 pen is made fresh after your order is placed, and each one is prepared and quality checked before dispatch. Independent third-party testing of SS-31 is under way. The batch Certificate of Analysis will be published here, and linked to your pen's batch number, as soon as results are verified. Read how we test and verify every batch on our Quality & Batch Verification page.
| Documentation status | Independent testing in progress |
|---|---|
| Test method | HPLC (purity and identity) |
| Analysis | Independent third-party laboratory, plus in-house QC on every pen |
| Verification | Batch number on every pen; COA linked by QR once published |
Storage conditions
- Shipped cold chain to keep the pen cool in transit
- Long-term: −20 °C in a temperature-controlled environment
- Short-term: keep cool and stable (2–8 °C) and away from direct light
- Keep the pen sealed when not in use
- Avoid repeated temperature changes (freeze–thaw cycles)
Handling guidance
- Check that the packaging and tamper seal are intact on arrival
- Handle as little as possible, using standard laboratory practice
- Record the batch number for traceability
- Follow any batch-specific guidance supplied with your order
What is SS-31?
SS-31, also called elamipretide, is a synthetic four-amino-acid peptide that concentrates at the inner mitochondrial membrane and binds cardiolipin. It has been studied in cell and animal models of mitochondrial function. Apexion supplies it for laboratory research only.
What is the difference between SS-31 and MOTS-c?
SS-31 is a synthetic tetrapeptide designed to target the inner mitochondrial membrane. MOTS-c is a natural 16-amino-acid peptide encoded in mitochondrial DNA that is studied mainly in metabolic signalling. Both are supplied for research use only.
How much SS-31 is in each pen?
Each pen contains 50 mg of SS-31 in one pre-filled research pen. Every pen comes from a single batch and carries its batch number.
Is SS-31 independently tested?
Every SS-31 pen is made fresh after your order is placed, so each one is prepared and quality checked to order rather than taken from old stock. Independent third-party testing of SS-31 is under way, and the batch Certificate of Analysis will be published as soon as the results are verified. Each pen carries a batch number, so its documentation can be traced.
Can SS-31 be used in humans or animals?
No. This product is not a medicine and is not licensed by the MHRA. It is supplied strictly for in-vitro laboratory research, and is not for human or veterinary use, diagnosis or treatment.
How should SS-31 be stored?
SS-31 is shipped cold chain. On arrival, keep the pen sealed and store it at −20 °C for long-term storage, away from heat and direct light. Handle it as little as possible and follow any batch-specific guidance supplied with your order.
Upsell
Frequently bought together
Bundle price
£269.98
£289.98
Save £20.00
Cross-sell
