GLP3-RTA 40mg
METABOLIC RESEARCH
Cagrilintide 10mg
Metabolic Research, Research Peptide Pens
One pre-filled 10mg Cagrilintide research pen for laboratory studies of appetite-related signalling.
£109.99Free UK tracked delivery
- Made fresh to order
- Batch documentation pending
- UK tracked delivery
- Made fresh to order: dispatched within 1 to 2 working days
- Results published when verified
Research Use Only
Cagrilintide 10mg is a long-acting synthetic analogue of amylin, a peptide hormone released alongside insulin, supplied in one pre-filled research pen. Every Cagrilintide pen is prepared to order in the UK and shipped cold chain by tracked delivery.
Cagrilintide was designed with sequence changes and a fatty-acid side chain that make it more stable and longer acting than native amylin. Our research compound guide covers related metabolic peptides, including GLP3-RTA.
How Cagrilintide is studied
Cagrilintide activates amylin receptors, which form when the calcitonin receptor pairs with a receptor activity-modifying protein (RAMP), and it also activates the calcitonin receptor itself. Laboratory studies have compared it with selective and non-selective agonists in receptor-signalling assays, and a dedicated tool compound has been developed for preclinical mode-of-action work.
5 key research areas
- Amylin receptor pharmacology. Receptor assays examined its activity at the three amylin receptor subtypes (AMY1–3).
- Calcitonin receptor signalling. It also activates the calcitonin receptor, which makes it a non-selective agonist within this receptor family.
- Preclinical tool compounds. A related tool compound, 0839, was characterised for mode-of-action studies of amylin analogues in rodent models.
- Peptide design and stability. Its development paper describes the sequence and acylation changes used to extend its half-life.
- Receptor selectivity. Receptor assays compared it with six selective and non-selective agonists across the calcitonin receptor family.
Selected published research
Peer-reviewed studies on Cagrilintide, with PubMed IDs:
- Kruse T, et al. (2021). Development of cagrilintide, a long-acting amylin analogue. Journal of Medicinal Chemistry. PMID 34288673
- Fletcher MM, et al. (2021). AM833 is a novel agonist of calcitonin family G protein-coupled receptors: pharmacological comparison with six selective and nonselective agonists. Journal of Pharmacology and Experimental Therapeutics. PMID 33727283
- Gabery S, et al. (2025). Characterization of 0839 – a tool compound for pre-clinical mode-of-action studies of amylin analogues such as cagrilintide. Life Sciences. PMID 40628316
These references describe chemical, receptor-assay and animal research on Cagrilintide, which is not licensed in the UK. They are cited as scientific background only and do not make this research material suitable for human use.
What arrives
10mg pen
One pre-filled Apexion research pen
One pre-filled Apexion research pen
Single compound
Cagrilintide, long-acting amylin analogue
Cagrilintide, long-acting amylin analogue
Protected packaging
Sealed and tamper-evident
Sealed and tamper-evident
Batch traceability
Batch number on every pen; independent testing in progress
Batch number on every pen; independent testing in progress
Preparation and UK dispatch
- Made fresh to order after checkout
- Prepared and quality checked before dispatch
- Tracked Royal Mail delivery across the UK
- UK-based product and documentation support
Simple, secure checkout
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Independent testing is in progress; results will be published only when verified evidence is available.
Research use only. Cagrilintide is supplied for in-vitro laboratory research by qualified researchers. It is not a medicine, is not licensed by the MHRA, and is not intended for human or veterinary use, diagnosis or treatment.
| Content | 10 mg Cagrilintide, one pre-filled research pen |
|---|---|
| Purity | Independent testing in progress; results published on verification |
| CAS | 1415456-99-3 |
| Molecular formula | C194H312N54O59S2 |
| Molecular weight | ~4409 g/mol |
| Form | Pre-filled research pen |
| Origin | UK-stocked, tracked Royal Mail dispatch |
| Intended use | Laboratory research only. |
Every Cagrilintide pen is made fresh after your order is placed, and each one is prepared and quality checked before dispatch. Independent third-party testing of Cagrilintide is under way. The batch Certificate of Analysis will be published here, and linked to your pen's batch number, as soon as results are verified. Read how we test and verify every batch on our Quality & Batch Verification page.
| Documentation status | Independent testing in progress |
|---|---|
| Test method | HPLC (purity and identity) |
| Analysis | Independent third-party laboratory, plus in-house QC on every pen |
| Verification | Batch number on every pen; COA linked by QR once published |
Storage conditions
- Shipped cold chain to keep the pen cool in transit
- Long-term: −20 °C in a temperature-controlled environment
- Short-term: keep cool and stable (2–8 °C) and away from direct light
- Keep the pen sealed when not in use
- Avoid repeated temperature changes (freeze–thaw cycles)
Handling guidance
- Check that the packaging and tamper seal are intact on arrival
- Handle as little as possible, using standard laboratory practice
- Record the batch number for traceability
- Follow any batch-specific guidance supplied with your order
What is Cagrilintide?
Cagrilintide is a long-acting synthetic analogue of amylin, a peptide hormone released alongside insulin. It acts on amylin and calcitonin receptors and has been studied in receptor assays and rodent models. Apexion supplies it for laboratory research only.
What is the difference between Cagrilintide and amylin?
Cagrilintide is a modified analogue of amylin. Changes to its sequence and an added fatty-acid side chain make it more stable and longer acting than native amylin, which breaks down quickly.
How much Cagrilintide is in each pen?
Each pen contains 10 mg of Cagrilintide in one pre-filled research pen. Every pen comes from a single batch and carries its batch number.
Is Cagrilintide independently tested?
Every Cagrilintide pen is made fresh after your order is placed, so each one is prepared and quality checked to order rather than taken from old stock. Independent third-party testing of Cagrilintide is under way, and the batch Certificate of Analysis will be published as soon as the results are verified. Each pen carries a batch number, so its documentation can be traced.
Can Cagrilintide be used in humans or animals?
No. Cagrilintide is not a medicine and is not licensed by the MHRA. It is supplied strictly for in-vitro laboratory research, and is not for human or veterinary use, diagnosis or treatment.
How should Cagrilintide be stored?
Cagrilintide is shipped cold chain. On arrival, keep the pen sealed and store it at −20 °C for long-term storage, away from heat and direct light. Handle it as little as possible and follow any batch-specific guidance supplied with your order.
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