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GROWTH HORMONE AXIS RESEARCH

CJC-1295 + IPAMORELIN 10MG

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One pre-filled 10mg research pen combining CJC-1295 (no DAC) 5mg and Ipamorelin 5mg.

4.9 · 20 Google reviews Research grade
£139.99Free UK tracked delivery
  • Made fresh to order
  • Batch documentation pending
  • UK tracked delivery
  • Order by 1pm on working days for same-day dispatch
  • Results published when verified

Research Use Only

CJC-1295 + Ipamorelin 10mg is a two-peptide research blend of CJC-1295 (no DAC) and ipamorelin, supplied in one pre-filled research pen with 5 mg of each. Every pen is prepared to order in the UK and shipped cold chain by tracked delivery.

The two peptides act on different receptors in the growth hormone axis, which is why they are often studied together. Read CJC-1295 vs ipamorelin for how they compare, and peptide stacks explained for how research blends are put together. For a full-length GHRH analogue, see tesamorelin.

Blend composition

CJC-1295 (no DAC) 5 mg · 29-amino-acid GHRH analogue (modified GRF 1-29)
Ipamorelin 5 mg · Synthetic pentapeptide, ghrelin-receptor agonist
Total 10 mg in one pre-filled research pen

How each component is studied

The two peptides in this blend act through different receptors in laboratory studies:

  • CJC-1295 (no DAC), also called modified GRF (1-29), is the first 29 amino acids of GHRH with four amino-acid substitutions that slow its breakdown. It acts on the GHRH receptor. Most published CJC-1295 data concern the related DAC form, which binds albumin and lasts far longer; the no-DAC form supplied here does not carry that albumin-binding group.
  • Ipamorelin is a synthetic pentapeptide that activates the ghrelin receptor (GHS-R1a). In pig and rat studies it released growth hormone without the rises in ACTH and cortisol seen with other secretagogues.

5 key research areas

  1. GHRH receptor signalling. Rat studies examined GHRH (1-29) analogues at the GHRH receptor on the anterior pituitary.
  2. Ghrelin receptor selectivity. Ipamorelin was characterised as a selective growth hormone secretagogue in pig and rat models.
  3. Pulsatile growth hormone release. Studies examined whether the natural pulse pattern of growth hormone persists during continuous GHRH receptor stimulation.
  4. Growth and IGF-1 models. CJC-1295 was studied in GHRH-knockout mice, a model lacking natural GHRH.
  5. Bone formation models. Ipamorelin was examined in adult rats given glucocorticoids, a model of reduced bone formation.

Selected published research

Peer-reviewed studies on each component, with PubMed IDs:

  1. Raun K, et al. (1998). Ipamorelin, the first selective growth hormone secretagogue. European Journal of Endocrinology. PMID 9849822
  2. Andersen NB, et al. (2001). The growth hormone secretagogue ipamorelin counteracts glucocorticoid-induced decrease in bone formation of adult rats. Growth Hormone & IGF Research. PMID 11735244
  3. Jetté L, et al. (2005). Human growth hormone-releasing factor (hGRF)1-29-albumin bioconjugates activate the GRF receptor on the anterior pituitary in rats: identification of CJC-1295 as a long-lasting GRF analog. Endocrinology. PMID 15817669
  4. Teichman SL, et al. (2006). Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults. Journal of Clinical Endocrinology and Metabolism. PMID 16352683
  5. Ionescu M, Frohman LA (2006). Pulsatile secretion of growth hormone (GH) persists during continuous stimulation by CJC-1295, a long-acting GH-releasing hormone analog. Journal of Clinical Endocrinology and Metabolism. PMID 17018654
  6. Alba M, et al. (2006). Once-daily administration of CJC-1295, a long-acting growth hormone-releasing hormone (GHRH) analog, normalizes growth in the GHRH knockout mouse. American Journal of Physiology. Endocrinology and Metabolism. PMID 16822960

These references describe laboratory, animal and early clinical research on the individual compounds, and most of the CJC-1295 papers studied the DAC form. None of them studied this blend, and none makes this research material suitable for human use.

Why a single-batch blend

  • Both compounds come from one batch, under one batch reference
  • One Certificate of Analysis will cover the whole blend once independent testing is complete
  • Fewer handling steps than preparing two separate compounds
  • Consistent composition from one order to the next

What arrives

10mg blend pen
One pre-filled Apexion research pen
Two-compound blend
CJC-1295 (no DAC) and ipamorelin, 5 mg each
Protected packaging
Discreet and tamper-evident
Batch traceability
Batch number on every pen; independent testing in progress

Preparation and UK dispatch

  • Made fresh to order after checkout
  • Prepared and quality checked before dispatch
  • Tracked Royal Mail delivery across the UK
  • UK-based product and documentation support

Simple, secure checkout

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Independent testing is in progress; results will be published only when verified evidence is available.

Source-material testing record

The submitted source-material blend report measured 4.95 mg ipamorelin and 5.19 mg CJC-1295 (modified GRF 1-29); CJC-1295 DAC was not detected. No purity percentage was reported.

Scope: This information concerns a submitted source-material sample. It does not certify an Apexion finished pen or establish a match to the pen batch.
View source-material record (PDF) →
The original laboratory report is available on request.

Research use only. This blend is supplied for in-vitro laboratory research by qualified researchers. It is not a medicine, is not licensed by the MHRA, and is not intended for human or veterinary use, diagnosis or treatment.

Research gradeLaboratory use only
Analytical statusIndependent testing in progress; results published on verification
Research use onlyNot for human consumption
Product presentation
CJC-1295 + IPAMORELIN 10MG

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