MELANOCORTIN RESEARCH
MT2 (Melanotan II) 10MG
One pre-filled 10mg MT2 research pen for laboratory studies of pigment production and cell signalling.
£89.99Free UK tracked delivery from £100
- Made fresh to order
- Batch documentation pending
- UK tracked delivery
- Made fresh to order: dispatched within 1 to 2 working days
- Results published when verified
Research Use Only
MT2 (Melanotan II) 10mg is a synthetic cyclic analogue of alpha-melanocyte-stimulating hormone (alpha-MSH), supplied in one pre-filled research pen. Every MT2 pen is prepared to order in the UK and shipped cold chain by tracked delivery.
MT2 was designed in the late 1980s as a cyclic lactam version of the alpha-MSH core sequence, making it more potent and longer acting than the natural hormone. It is closely related to PT-141, and our research compound guide covers other melanocortin peptides such as KPV.
How MT2 is studied
MT2 is a non-selective agonist at several melanocortin receptors, including MC1R, MC3R, MC4R and MC5R. Its activity at MC1R on melanocytes made it a reference compound in melanogenesis research. Its activity at MC3R and MC4R in the brain made it a common tool for studying central melanocortin signalling, including feeding behaviour in mouse models.
5 key research areas
- Melanocortin receptor pharmacology. MT2 is used as a non-selective reference agonist across the MC1R, MC3R, MC4R and MC5R receptors.
- Melanogenesis. Its MC1R activity has been studied in melanocyte and skin pigmentation models.
- Central melanocortin signalling. Mouse studies used MT2 to examine MC4R-mediated control of feeding, including in agouti mouse models.
- Peptide design. The cyclic lactam bridge was studied for its effect on potency and duration of action compared with linear analogues.
- Early clinical pharmacology. A pilot phase I study and later reviews describe its pharmacology as an investigational compound.
Selected published research
Peer-reviewed studies on MT2, with PubMed IDs:
- Al-Obeidi F, et al. (1989). Potent and prolonged acting cyclic lactam analogues of alpha-melanotropin: design based on molecular dynamics. Journal of Medicinal Chemistry. PMID 2555512
- Dorr RT, et al. (1996). Evaluation of melanotan-II, a superpotent cyclic melanotropic peptide in a pilot phase-I clinical study. Life Sciences. PMID 8637402
- Fan W, et al. (1997). Role of melanocortinergic neurons in feeding and the agouti obesity syndrome. Nature. PMID 8990120
- Hadley ME, et al. (1998). Discovery and development of novel melanogenic drugs. Melanotan-I and -II. Pharmaceutical Biotechnology. PMID 9760697
These references describe laboratory, animal and early clinical research on MT2 as an investigational compound. They are cited as scientific background only and do not make this research material suitable for human use.
What arrives
10mg pen
One pre-filled Apexion research pen
One pre-filled Apexion research pen
Single compound
MT2 (Melanotan II), cyclic alpha-MSH analogue
MT2 (Melanotan II), cyclic alpha-MSH analogue
Protected packaging
Sealed and tamper-evident
Sealed and tamper-evident
Batch traceability
Batch number on every pen; independent testing in progress
Batch number on every pen; independent testing in progress
Preparation and UK dispatch
- Made fresh to order after checkout
- Prepared and quality checked before dispatch
- Tracked Royal Mail delivery across the UK
- UK-based product and documentation support
Simple, secure checkout
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Independent testing is in progress; results will be published only when verified evidence is available.
Research use only. This product is supplied for in-vitro laboratory research by qualified researchers. It is not a medicine, is not licensed by the MHRA, and is not intended for human or veterinary use, diagnosis or treatment.
| Content | 10 mg MT2 (Melanotan II), one pre-filled research pen |
|---|---|
| Purity | Independent testing in progress; results published on verification |
| CAS | 121062-08-6 |
| Molecular formula | C50H69N15O9 |
| Molecular weight | ~1024.2 g/mol |
| Form | Pre-filled research pen |
| Origin | UK-stocked, tracked Royal Mail dispatch |
| Intended use | Laboratory research only. |
Every MT2 pen is made fresh after your order is placed, and each one is prepared and quality checked before dispatch. Independent third-party testing of MT2 is under way. The batch Certificate of Analysis will be published here, and linked to your pen's batch number, as soon as results are verified. Read how we test and verify every batch on our Quality & Batch Verification page.
| Documentation status | Independent testing in progress |
|---|---|
| Test method | HPLC (purity and identity) |
| Analysis | Independent third-party laboratory, plus in-house QC on every pen |
| Verification | Batch number on every pen; COA linked by QR once published |
Storage conditions
- Shipped cold chain to keep the pen cool in transit
- Long-term: −20 °C in a temperature-controlled environment
- Short-term: keep cool and stable (2–8 °C) and away from direct light
- Keep the pen sealed when not in use
- Avoid repeated temperature changes (freeze–thaw cycles)
Handling guidance
- Check that the packaging and tamper seal are intact on arrival
- Handle as little as possible, using standard laboratory practice
- Record the batch number for traceability
- Follow any batch-specific guidance supplied with your order
What is MT2?
MT2, or Melanotan II, is a synthetic cyclic analogue of alpha-MSH that acts on several melanocortin receptors. It has been studied in melanogenesis and central melanocortin signalling models. Apexion supplies it for laboratory research only.
What is the difference between MT2 and PT-141?
The two are closely related cyclic peptides. PT-141 (Bremelanotide) has the same ring structure as MT2 but ends in a free acid rather than an amide, and it is studied mainly for central MC4R signalling rather than pigmentation.
How much MT2 is in each pen?
Each pen contains 10 mg of MT2 in one pre-filled research pen. Every pen comes from a single batch and carries its batch number.
Is MT2 independently tested?
Every MT2 pen is made fresh after your order is placed, so each one is prepared and quality checked to order rather than taken from old stock. Independent third-party testing of MT2 is under way, and the batch Certificate of Analysis will be published as soon as the results are verified. Each pen carries a batch number, so its documentation can be traced.
Can MT2 be used in humans or animals?
No. This product is not a medicine and is not licensed by the MHRA. It is supplied strictly for in-vitro laboratory research, and is not for human or veterinary use, diagnosis or treatment.
How should MT2 be stored?
MT2 is shipped cold chain. On arrival, keep the pen sealed and store it at −20 °C for long-term storage, away from heat and direct light. Handle it as little as possible and follow any batch-specific guidance supplied with your order.
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