PT-141 10MG
One pre-filled 10mg PT-141 research pen for laboratory studies of cell signalling.
- Made fresh to order
- Batch documentation pending
- UK tracked delivery
- Order by 1pm on working days for same-day dispatch
- Results published when verified
Research Use Only
PT-141 10mg (bremelanotide) is a synthetic cyclic heptapeptide that acts on melanocortin receptors, supplied in one pre-filled research pen. Every PT-141 pen is prepared to order in the UK and shipped cold chain by tracked delivery.
PT-141 is closely related to MT2 (Melanotan II): it shares MT2’s ring structure but ends in a free carboxylic acid instead of an amide. Our research compound guide covers other melanocortin peptides, including KPV.
How PT-141 is studied
PT-141 is an agonist mainly at the MC4R and MC3R melanocortin receptors, which are found in the hypothalamus and other brain regions. Research has focused on how central melanocortin signalling influences behaviour, using rodent behavioural models. It has also been developed elsewhere as a medicine, and reviews describe its clinical pharmacology.
5 key research areas
- MC4R and MC3R pharmacology. PT-141 is studied as an agonist at the central melanocortin receptors MC4R and MC3R.
- Central nervous system signalling. Studies examine how melanocortin pathways in the hypothalamus influence behaviour.
- Rodent behavioural models. Female rat studies examined the effect of melanocortin receptor activation on sexual behaviour.
- Structure-activity relationships. Its relationship to MT2 is used to compare how small structural changes affect receptor activity.
- Clinical development. Reviews summarise its development as a medicine elsewhere; this product is research material only.
Selected published research
Peer-reviewed studies and reviews on PT-141, with PubMed IDs:
- Molinoff PB, et al. (2003). PT-141: a melanocortin agonist for the treatment of sexual dysfunction. Annals of the New York Academy of Sciences. PMID 12851303
- Pfaus JG, et al. (2004). Selective facilitation of sexual solicitation in the female rat by a melanocortin receptor agonist. Proceedings of the National Academy of Sciences of the USA. PMID 15226502
- Hadley ME, Dorr RT (2006). Melanocortin peptide therapeutics: historical milestones, clinical studies and commercialization. Peptides. PMID 16412534
- Dhillon S, Keam SJ (2019). Bremelanotide: first approval. Drugs. PMID 31429064
These references describe laboratory, animal and clinical research on PT-141 (bremelanotide). They are cited as scientific background only and do not make this research material suitable for human use.
What arrives
One pre-filled Apexion research pen
PT-141 (bremelanotide), cyclic melanocortin peptide
Discreet and tamper-evident
Batch number on every pen; independent testing in progress
Preparation and UK dispatch
- Made fresh to order after checkout
- Prepared and quality checked before dispatch
- Tracked Royal Mail delivery across the UK
- UK-based product and documentation support
Simple, secure checkout
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Independent testing is in progress; results will be published only when verified evidence is available.
Research use only. This product is supplied for in-vitro laboratory research by qualified researchers. It is not a medicine, is not licensed by the MHRA, and is not intended for human or veterinary use, diagnosis or treatment.
| Content | 10 mg PT-141 (bremelanotide), one pre-filled research pen |
|---|---|
| Purity | Independent testing in progress; results published on verification |
| CAS | 189691-06-3 |
| Molecular formula | C50H68N14O10 |
| Molecular weight | ~1025.2 g/mol |
| Form | Pre-filled research pen |
| Origin | UK-stocked, tracked Royal Mail dispatch |
| Intended use | Laboratory research only. Not for human consumption. |
Every PT-141 pen is made fresh after your order is placed, and each one is prepared and quality checked before dispatch. Independent third-party testing of PT-141 is under way. The batch Certificate of Analysis will be published here, and linked to your pen's batch number, as soon as results are verified. Read how we test and verify every batch on our Quality & Batch Verification page.
| Documentation status | Independent testing in progress |
|---|---|
| Test method | HPLC (purity and identity) |
| Analysis | Independent third-party laboratory, plus in-house QC on every pen |
| Verification | Batch number on every pen; COA linked by QR once published |
Storage conditions
- Shipped cold chain to keep the pen cool in transit
- Long-term: −20 °C in a temperature-controlled environment
- Short-term: keep cool and stable (2–8 °C) and away from direct light
- Keep the pen sealed when not in use
- Avoid repeated temperature changes (freeze–thaw cycles)
Handling guidance
- Check that the packaging and tamper seal are intact on arrival
- Handle as little as possible, using standard laboratory practice
- Record the batch number for traceability
- Follow any batch-specific guidance supplied with your order
What is PT-141?
PT-141, also called bremelanotide, is a synthetic cyclic peptide that acts mainly on the MC4R and MC3R melanocortin receptors in the brain. It has been studied in rodent behavioural models of central melanocortin signalling. Apexion supplies it for laboratory research only.
What is the difference between PT-141 and MT2?
PT-141 has the same ring structure as MT2 but ends in a free acid rather than an amide. MT2 is a broader melanocortin agonist also studied in pigmentation models, while PT-141 research focuses on central MC4R signalling.
How much PT-141 is in each pen?
Each pen contains 10 mg of PT-141 in one pre-filled research pen. Every pen comes from a single batch and carries its batch number.
Is PT-141 independently tested?
Every PT-141 pen is made fresh after your order is placed, so each one is prepared and quality checked to order rather than taken from old stock. Independent third-party testing of PT-141 is under way, and the batch Certificate of Analysis will be published as soon as the results are verified. Each pen carries a batch number, so its documentation can be traced.
Can PT-141 be used in humans or animals?
No. This product is not a medicine and is not licensed by the MHRA. It is supplied strictly for in-vitro laboratory research, and is not for human or veterinary use, diagnosis or treatment.
How should PT-141 be stored?
PT-141 is shipped cold chain. On arrival, keep the pen sealed and store it at −20 °C for long-term storage, away from heat and direct light. Handle it as little as possible and follow any batch-specific guidance supplied with your order.
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